Top 10 Best Nasal Sprays for Allergies | Buoy (2024)

Nasal sprays are an effective solution for alleviating allergy symptoms by reducing swelling and clearing mucus directly in the nasal passages where irritation from allergens often occurs. Some of them work within 15 minutes after use. Their localized treatment minimizes side effects compared to oral medications and provides fast, effective relief at the source of the problem.

This article will discuss the 10 best nasal sprays to help relieve allergy symptoms. We’ll also discuss what makes each suitable and how they can help you feel better.

Types of Nasal Sprays for Allergies

Nasal sprays are liquid medications squirted into the nasal passages to alleviate nasal congestion commonly caused by colds or allergies. They work by relieving stuffiness and reducing nasal discharge. These sprays deliver the medication in a fine mist, released from a pressurized container with a valve for adequate symptom relief.

​​There are a variety of nasal sprays on the market with different mechanisms of action. Knowing the differences is essential in making an informed choice on allergy relief. Here are the different types of nasal sprays that combat allergy symptoms.

1. Antihistamine Sprays

These sprays target nasal allergy symptoms by blocking histamine. Common side effects of antihistamine nasal sprays include the following:

  • Bitter taste
  • Dizziness
  • Drowsiness
  • Dry mouth and nose

You can get these with a prescription; some are also available over the counter. Prescription options include the following medications:

  • Patanase (Olopatadine)
  • Astelin (Azelastine)

An example of an OTC antihistamine is Astepro (the OTC version of Astelin)

2. Steroid Nasal Sprays

These are preferred for various allergy symptoms, especially for reducing inflammation and congestion. They work best when used regularly, typically once daily for a few weeks.

Common side effects of using steroid nasal sprays include the following:

  • Headaches
  • Nosebleeds
  • Nasal irritation
  • Cough

If you've had nose surgery, an untreated sinus infection, tuberculosis, or if you're pregnant or breastfeeding, talk to a doctor before using steroid nasal sprays.

Examples of steroid nasal sprays in the market are:

  • Rhinocort (Budesonide)
  • Flonase (Fluticasone)
  • Nasonex (Mometasone)
  • Nasacort (Triamcinolone)
  • Veramyst (Fluticasone furoate)

3. Mast Cell Inhibitor Sprays

Mast cell inhibitor nasal sprays work by helping prevent the release of histamine, reducing allergy symptoms when used consistently. They help control allergic reactions over time but don't provide quick relief. Still, they're essential for long-term allergy management.

Typical side effects are the following:

  • Sneezing
  • Nasal burning or irritation
  • Unpleasant taste

Given their safety profile, mast cell inhibitor sprays suit many users, including children and adults.

An example of a mast cell inhibitor nasal spray available OTC is Cromolyn sodium (Nasalcrom).

4. Decongestant Sprays

Decongestant nasal sprays provide immediate relief for nasal congestion but should be used short-term to avoid rebound congestion. It is generally advisable to avoid use beyond 3-4 consecutive days before taking a break from use.

These sprays shrink blood vessels in the nose to lessen congestion, but they don't stop sneezing or a runny nose. They give quick relief and are often used for sudden nasal blockage.

Common side effects associated with decongestant sprays are the following:

  • Sneezing
  • Nausea
  • Sinus pains
  • Vomiting
  • Dryness or burning in the nose
  • Rebound congestion with prolonged use, which can be difficult to treat

Contraindications for decongestant sprays include individuals who have the following conditions:

  • Cardiovascular conditions, such as high blood pressure or heart disease
  • Overactive thyroid or enlarged prostate
  • Pregnant women should consult a doctor before use

Some of the decongestant nasal sprays found on the market are the following:

  • Afrin (Oxymetazoline)
  • Zicam (Oxymetazoline)
  • Sinex (Oxymetazoline)
  • Dristan (Phenylephrine)
  • Neo-Synephrine (Phenylephrine)

5. Saline Sprays

Saline nasal sprays moisturize the nasal passages, which helps to thin mucus and moisturize the nasal lining. They can be used without side effects except for possible mild irritation.

Common side effects are minimal but can include the following:

  • Mild nasal irritation
  • A brief stinging sensation if the nasal passages are very dry

Examples of saline nasal spray products include the following:

  • Arm & Hammer Simply Saline (Sodium chloride, sodium bicarbonate)
  • Ayr (Sodium chloride 0.65%)
  • Amazon Basic Care Premium Saline Nasal Moisturizing Spray
  • Ocean nasal

6. Anticholinergic Sprays

Anticholinergic nasal sprays help dry up a runny nose by blocking acetylcholine, making them effective for allergic and nonallergic rhinitis.

Side effects associated with anticholinergic sprays can include the following:

  • Dryness of the nasal mucosa
  • Irritation or burning sensation in the nose
  • Headache
  • Dry mouth

People with narrow-angle glaucoma or trouble urinating should be careful with anticholinergics, and they're recommended for children.

The market offers Atrovent (Ipratropium bromide, 0.03%) as a prescription anticholinergic nasal spray. There are no OTC anticholinergic nasal sprays available.

Top 10 Best Nasal Sprays for Allergies

We understand the importance of effective allergy relief, especially in wanting to feel comfortable doing daily tasks without allergy symptoms. That's why we have meticulously researched and compiled a list of the top 10 best nasal sprays for allergies.

Our selection is based on carefully evaluating factors such as the following:

  • Efficacy
  • Active Ingredient
  • Potency
  • Each of administration
  • Potential side effects

Whether you're seeking immediate relief from acute symptoms or a long-term solution for managing your allergies, our top recommendations are detailed below.

Top 10 Best Nasal Sprays for Allergies | Buoy (2024)

FAQs

What is the most effective nasal spray for allergies? ›

Experts say that over-the-counter (OTC) anti-inflammatory nasal sprays—such as FLONASE nasal sprays or Nasacort® 24 Hour—are the most effective form of nasal allergy symptom relief.

What is the best medicine for severe allergies? ›

Nasal steroids are often the first treatment doctors recommend. Some steroid sprays require a doctor's prescription, but three of them, budesonide (Rhinocort Allergy), fluticasone (Flonase), and triamcinolone (Nasacort Allergy 24HR), do not.

What nasal spray can you use everyday? ›

Nasal steroids sprays (Flonase®, Nasocort®, Nasonex®, etc. ) are safe to use on a daily basis and are now largely over-the-counter. These sprays are non-addictive and typically do not cause any long term changes to the nasal passages.

What is the strongest antihistamine over-the-counter? ›

What is the most effective antihistamine? Among second-generation antihistamines, Zyrtec is the strongest and most effective, says Dr. Staiger. The first-generation antihistamine Benadryl is also highly effective, but drowsiness is a limiting factor (unless you are looking to utilize it as a sleep aid), he says.

What is the best nasal spray for seniors? ›

Steroid nasal sprays, such as Flonase (fluticasone propionate), are some of the best allergy medicines for older adults. Astepro (azelastine) nasal spray, and non-drowsy oral antihistamines, such as Allegra (fexofenadine) are also first-choice options. All of these allergy medications are safe for older adults.

What nasal sprays do doctors prescribe? ›

They're often the first drug recommended for allergies, but it takes about a week before you'll notice your symptoms getting better. Examples of steroid nasal sprays available by prescription include beclomethasone (Beconase, Qnasl), ciclesonide (Zetonna), fluticasone furoate (Veramyst), and mometasone (Nasonex).

What is the safest antihistamine for long term use? ›

Non-drowsy options like loratadine and cetirizine are among the safest choices for long-term allergy relief. Both medications work by blocking the effects of histamine, and people generally tolerate them well.

How to cure allergic rhinitis permanently? ›

There is no cure for allergic rhinitis, but the effects of the condition can be lessened with the use of nasal sprays and antihistamine medications.

What is the strongest natural antihistamine? ›

What is the most powerful natural antihistamine? Researchers haven't yet established any natural product as the “best” or “most powerful.” Natural antihistamines with the most research backing their use include stinging nettle, vitamin C, quercetin, butterbur, bromelain, and probiotics.

Is Nasacort or Flonase better? ›

Official answer. Nasacort and Flonase are equally effective, safe, and well tolerated for the treatment of allergic rhinitis. Therefore the choice of either Nasacort or Flonase comes down to personal preference, availability or price.

What is the best nasal spray for blocked sinuses? ›

For nasal congestion, we recommend Otrivine Sinusitis Relief Nasal Spray. The spray delivers an exact medicated dose of xylometazoline hydrochloride inside the nostril to relieve the nasal congestion as well as helping to ease the sinusitis pain and pressure that you may be feeling.

Which is better, Flonase or Nasonex? ›

Official answer. The difference is Flonase is available over-the-counter (OTC) and Nasonex is prescription only. There is no difference in their effect or side effects. Flonase and Nasonex are both corticosteroid nasal sprays that are effective at treating hay fever, perennial allergic rhinitis and allergies.

What do doctors prescribe for severe allergies? ›

  • Beclomethasone (Beconase AQ, Qnasl)
  • Budesonide (generic)
  • Ciclesonide (Omnaris, Zetonna)
  • Flunisolide (generic)
  • Fluticasone furoate (Flonase Sensimist)
  • Fluticasone propionate (Flonase Allergy Relief)
  • Mometasone (Nasonex 24HR Allergy)
  • Triamcinolone (GoodSense Nasal Allergy, Nasacort Allergy 24HR)

What is the best antihistamine for older adults? ›

The American Academy of Allergy, Asthma, and Immunology (AAAAI) recommends second and third-generation antihistamines as the safest option for older adults, as they cause fewer side effects. They include loratadine (Claritin) and fexofenadine (Allegra).

What is the most effective allergy medicine? ›

Antihistamines, such as Claritin (loratadine), can provide quick relief and can help prevent symptoms if taken every day. Nasal steroids, such as Flonase (fluticasone propionate), are generally the most effective allergy medicines but can take up to 2 weeks to fully work.

Is Nasacort or Flonase better for allergies? ›

Official answer. Nasacort and Flonase are equally effective, safe, and well tolerated for the treatment of allergic rhinitis. Therefore the choice of either Nasacort or Flonase comes down to personal preference, availability or price.

Which is better, Afrin or Flonase? ›

Is Afrin or Flonase better? Afrin provides a faster response to congestion with an onset of action within 10 minutes. It is not recommended for use longer than three days, however. Flonase is slower to relieve congestion symptoms but can be used safely long term.

Which is the best nasal spray for a blocked nose? ›

For nasal congestion, we recommend Otrivine Sinusitis Relief Nasal Spray. The spray delivers an exact medicated dose of xylometazoline hydrochloride inside the nostril to relieve the nasal congestion as well as helping to ease the sinusitis pain and pressure that you may be feeling.

Why is Flonase discontinued? ›

The nasal spray has been found to contain small glass particles which could block the actuator and impact the functionality of the pump. There is a potential for patients to be exposed to the glass particles and mechanical irritation cannot be ruled out.

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